Mock assignment (2.5 points)
The topic: Strategies to fight the Novel Coronavirus SARS-CoV2
1-Format: (1 page, excluding references)
I.Background: Describe SARS-CoV2 structure and virus molecules useful to invade host cells (1/4 page) (0.4 point).
II.Pathogenesis: Describe how SARS-CoV2 invades human cells, which are the routes of invasion and what is the mode of replication inside the cells. Pay attention to WHICH CELLS the virus invades and uses to replicate preferentially (1/2 page) (0.8 point).
III.Strategy to stop SARS-CoV2: Now that you know how and where SARS-CoV2 acts in your cells, take advantage of this knowledge and what you have learnt in class to design your own strategy to inhibit SARS-CoV2 infection and/or replication. You are strongly encouraged to develop your thoughts and ideas to fight the virus (1/4 page) (0.4 point).
2-References (0.4 point): Include at least THREE PEER-REVIEWED REFERENCES (the source of the information you used to write your report) in the following Format:
Stanchev S, Stamenov N, Kirkov V, Dzhambazova E, Nikolov D, Paloff A. 2020. Differential collagen expression in kidney and heart during hypertension. Nature
RESOURCES FOR STUDENTS
How SARS-CoV-2 Works
SARS-CoV-2 (Covid-19) Infection Process
The Coronavirus Replication Cycle (detailed)
Biology of SARS-CoV-2: Evolution
Interview with Dr. Anthony Fauci: Dr. Fauci offers 2021 forecast on COVID-19 vaccines, treatments
Coronavirus biology and replication: implications for SARS-CoV-2 (pdf of the article uploaded in Blackboard)
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