How to Prepare the REVIEW of the article “ The p53 Orchestra….”
Read the scientific article. Make notes summarizing key ideas and noting critical portions of the text.
The review should be 5 pages, single-spaced or 1.5 spaces using a standard 12-point font (such as Times New Roman).
As before, please include NO MORE THAN 1 FIGURE.
Please address the following points in your review:
In 300-500 describe the process of UBIQUITINATION. What is E1, E2 & E3? What is the role of Mdm2 and/or Mdmx in the process?
What is the role that Mdm2 and Mdmx play in p53 stability? Be as detailed as you can.
Discuss, briefly, the multiple cell signaling cascades that converge on Mdm2 and Mdmx (Figure 4).
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