Pharmacotherapy for Cardiovascular Disorders

3 questions

• Explain how the factor you selected      might influence the pharmacokinetic and pharmacodynamic processes in the      patient from the case study you were assigned.
• Describe how changes in the      processes might impact the patient’s recommended drug therapy. Be specific      and provide examples.
• Explain how you might improve the patient’s      drug therapy plan and explain why you would make these recommended      improvements.

Patient Scenario (Case study)

Patient AO has a history of obesity and has recently gained 9 pounds. The patient has been diagnosed with hypertension and hyperlipidemia. Drugs currently prescribed include the following:

• Atenolol 12.5 mg daily
• Doxazosin 8 mg daily
• Hydralazine 10 mg qid
• Sertraline 25 mg daily
• Simvastatin 80 mg daily
• Review the Resources for this      module and consider the impact of potential pharmacotherapeutics for      cardiovascular disorders introduced in the media piece.
• Review the case study assigned by your Instructor for this Assignment.
• Select one the following factors: genetics, gender, ethnicity, age, or behavior factors.
• Reflect on how the factor you selected might influence the patient’s pharmacokinetic and pharmacodynamic processes.
• Consider how changes in the pharmacokinetic and pharmacodynamic processes might impact      the patient’s recommended drug therapy.
• Think about how you might improve the patient’s drug therapy plan based on the      pharmacokinetic and pharmacodynamic changes. Reflect on whether you would      modify the current drug treatment or provide an alternative treatment      option for the patient.
• All other factors were purposely omitted from the case study.  As you read through your course materials, please feel free to add those factors that you’d like to further discuss that may affect the decisions that you will make for this patient.  For example, if you’d like to discuss how the factor age will affect your choices, include in your paper that your patient is a 86 year old male.  Or if you’d like to provide details of how gender plays a role in what treatment the patient will receive, include that your patient is a female.