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Mendel and Human Genetics

COLLAPSE

Mendel did most of his work using pea plants and was studding seven different characteristics, each with two contrasting traits [1]. Morgan rediscovered his laws of inheritance and further the knowledge using Drosophila as a model organism. Later discoveries confirmed that human heredity is regulated by the same laws of inheritance. Many of our characteristics are polygenic, however a number of them are controlled by a single gene, and Mendel’s work is a “solid foundation for our current understanding of single-gene diseases in humans” [2].

Please search in the literature and present human disorder(s) that are following Mendelian type of inheritance.

1. https://opentextbc.ca/conceptsofbiology1stcanadianedition/chapter/8-1-mendels-experiments/

2. Chial, H. (2008) Mendelian genetics: Patterns of inheritance and single-gene disorders. Nature Education 1(1):63.

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