1. Describe briefly Boyle’s law, gas diffusion law,
Dalton’s law and explain how they apply to respiration in the human body.
2.
In your own words:
a.
Explain what gas exchange is, how are gases
exchanged, and the three factors that influence gas exchange in the lung
(external respiration).
b.
Describe how red blood cells participate in the
loading and unloading of oxygen and carbon dioxide at the respiratory membrane
and in the tissues. Make sure to include the role of two important proteins:
hemoglobin and carbonic anhydrase.
3. Explain the relation between PCO2 and
pH (include chemical equation). Why variations in PCO2 have more
impact on depth and rate of breathing than variation of PO2?
4.
Describe the filtration membrane. Explain the
features that make filtration a passive process. What component of the blood
end up in the filtrate? What pressures are promoting filtration? What happens
to the net filtration pressure and the glomerular filtration rate of blood pressure
in the afferent arteriole increases? How does that explain the relation between
BP and total volume of blood described in chapter 19 (long term regulation of
BP)
5.
In your own words, explain how filtrate becomes
urine. Mention the two steps of re-absorption and secretion, and the specificity
in each part of the tubule (PCT, Nephron loop, DTC, collecting duct). Include
where water, Na+ and K+ are secreted and reabsorbed, and what are the main
controls for each.
6.
Discuss the permeabilities of different sections
of the nephron loop and how they participate in creating a countercurrent
multiplier. How is the osmotic gradient created by this countercurrent used in
the collecting duct to concentrate or dilute urine and to regulate the volume
of urine?
7.
How is Na+ level in body fluids regulated?
Mention the Renin / Angiotensin / Aldosterone system (RAAS) and ANP. Emphasize
the role of aldosterone in the regulation of Na+ content and link it to blood
volume and blood pressure.
8.
List the different cells of the JGC, their
location and their function.
9.
Acidosis and alkalosis can result from the
metabolism or respiration. For each type, explain what the compensatory
mechanisms are.
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